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SKU: 126ERS

293A Human Specialized Cells

Engineered / Reporter / Stable Expression Cells > Kidney & Urinary Cells

Product Type: Human Kidney Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Kidney

$1,249.00
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Cell Name: 293A

The HEK 293A cell line is an immortalized line of primary human embryonic kidney cells transformed by sheared human Ad5 DNA.&Nbsp;The 293A Cell Line is a subclone of the 293 Cell Line and has a relatively flat morphology, strongly adheres to plastic dishes.

  • Description
    293A is a subclone of human embryonic kidney (HEK) 293 cell line, originally derived from fetal kidney fibroblasts transformed with adenovirus type 5 (Ad5). This adherent cell line exhibits epithelial-like morphology with adherent culture properties. These adherent cells exhibit a flat, monolayer growth pattern. 293A retains stable integration of the adenoviral E1 gene, enabling constitutive expression of E1a and E1b proteins, which supports efficient replication of E1-deleted adenoviral vectors. Additionally, 293A expresses an aberrant vitronectin receptor composed of integrin β1 and α-v subunits, enhancing cell adhesion and surface interactions. The cell line’s genetic and morphology features make it particularly valuable for viral plaque assays and adenovirus vector development.
  • Product Name
    293A
  • Product Type
    Human Kidney Cell Lines
  • Species
    Human
  • Product Type
    Human Kidney Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    293A cells are a powerful platform for the streamlined production, amplification, and titration of recombinant adenovirus vectors, especially those that are replication-incompetent. Their stable expression of adenoviral E1 proteins supports high-efficiency viral packaging, making them essential for researchers engaged in gene therapy, vaccine development and viral vector engineering. 293A is widely used in transfection assays and is ideal for precise screening and optimization of adenoviral constructs in both biomedical research and preclinical development.
  • Size/Quantity
    1 vial
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    2

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