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SKU: 0095ATC

8505C Human Thyroid Thyroid Cancer Epithelial Cells


Tumor Cell Lines > Thyroid Cancer Cell Lines

Product Type: Human Thyroid Cancer Cell Lines

Species: Human

Cell Type: Epithelial Cells

Source Organ: Thyroid


Regular price $1,249.00

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Cell Name: 8505C

Human thyroid carcinoma, undifferentiated. Established from undifferentiated thyroid carcinomas of a 78 year old female patient. Pathologically this primary carcinoma tissue contained residual well differentiated components.

  • Description
    8505C is a human thyroid carcinoma cell line that was originally isolated from a 78-year-old female patient with anaplastic thyroid carcinoma. 8505C exhibits epithelial-like morphology and adherent culture properties. Genetic analysis identified a specific point mutation in codon 248 of the p53 gene, characterized by a C:G to G:C transversion. 8505C serves as a valuable model for studying thyroid cancer and p53-related tumor mechanisms.
  • Product Name
    8505C
  • Product Type
    Human Thyroid Cancer Cell Lines
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Thyroid
  • Disease
    Thyroid Cancer
  • Product Type
    Human Thyroid Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The 8505C cell line plays a critical role in thyroid cancer research. It is frequently used to evaluate potential drugs that induce or inhibit apoptosis in thyroid carcinoma cells. Moreover, it supports studies on the involvement of p53 mutations in malignant transformation, providing insight into the molecular pathways driving thyroid cancer progression and contributing to the development of new therapeutic approaches.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    RPMI 1640 + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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