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SKU: 0563ATC

A-253 Human Submaxillary Salivary Gland Cancer Epithelial Cells

Tumor Cell Lines > Head & Neck Cancer Cell Lines

Product Type: Human Salivary Cancer Cell Lines

Species: Human

Cell Type: Epithelial Cells

Source Organ: Other

$1,249.00
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Cell Name: A-253

The A253 line is one of thirteen to be isolated and partially characterized through trial studies on a series of 200 human tumors.

  • Description
    A253 is a human salivary gland carcinoma cell line that was originally isolated from the submaxillary salivary gland. A253 exhibits epithelial-like morphology and adherent culture properties. This cell line is near triploid with at least 6 markers. It is one of thirteen series partially characterized by a comprehensive study involving 200 human tumors. A253 is tumorigenic.
  • Product Name
    A-253
  • Product Type
    Human Salivary Cancer Cell Lines
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Submaxillary Salivary Gland
  • Disease
    Cancer
  • Product Type
    Human Salivary Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    A253 cells enable cancer research on tumor growth, metastasis, and drug resistance mechanisms while supporting HNSCC drug development through efficacy/toxicity testing. They facilitate cell signaling studies of growth/differentiation/apoptosis pathways and epigenetic research into cancer progression. These cells serve as in vitro models for assessing drug/chemical/radiation effects and studying cellular processes. Additionally, A253 cells advance new HNSCC therapies (e.g., anti-EGFR immunotoxins), evaluate drug resistance mechanisms, investigate cell communication (muscarinic/β-adrenergic receptors), probe tumor metabolism for therapeutic targeting, study laminin-mediated adhesion/differentiation, evaluate sonodynamic therapy’s apoptotic efficacy, and analyze calcium mobilization mechanisms.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    McCoy’s 5a Medium + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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