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SKU: 0902ATC

B16-F10 Mouse Skin Melanoma Epithelial Cells

Tumor Cell Lines > Melanoma Cell Lines

Product Type: Mouse Melanoma Cell Lines

Species: Mouse

Cell Type: Epithelial Cells

Source Organ: Skin

$1,249.00
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Cell Name: B16-F10

Confirmed as a murine cell line. Tests for microbial contamination were negative.

  • Description
    B16-F10 is an animal tumor cell line that was originally isolated from the skin tissue of the 10th serial passage of the B16-F0 parent cell line in male C57BL/6 mice with mouse melanoma. These cells were isolated based on their remarkable ability to generate lung colonies following intravenous injection. B16-F10 exhibits epithelial-like morphology with spindle-shaped and adherent culture properties. B16-F10 is tumorigenic and demonstrates a propensity for lung metastasis. Upon introduction into mouse skin, these cells demonstrate a perivascular predominance in VEGF expression across multiple vessels.
  • Product Name
    B16-F10
  • Product Type
    Mouse Melanoma Cell Lines
  • Species
    Mouse
  • Cell Type
    Epithelial-like
  • Source Organ
    Skin
  • Disease
    Melanoma
  • Product Type
    Mouse Melanoma Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The B16-F10 cell line holds a pivotal role in advancing skin cancer research, with a specific emphasis on the intricate realm of metastasis. Their distinctive profile, marked by low immunogenicity and remarkable aggressiveness, positions them as a cornerstone in studies related to murine tumor immunotherapy. Furthermore, they serve as a crucial tool for deciphering the complex factors governing the successful implantation and subsequent survival of B16 melanoma. Moreover, these cells provide a reliable platform for evaluating the inhibitory effects of various agents on murine melanoma metastasis, allowing for a comprehensive understanding of the underlying mechanisms at play.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    DMEM + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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