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SKU: 0900ATC

BALL-1 Human Peripheral Blood Leukemia Immune Cells

Tumor Cell Lines > Leukemia Cell Lines

Product Type: Human Leukemia Cell Lines

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: BALL-1

Acute lymphoblastoid leukemia (ALL).

  • Description
    BALL-1 is a human  B-cell line that was originally isolated from the peripheral blood of a 14-year-old male patient with acute T-cell leukemia. BALL-1 exhibits lymphoblast-like morphology and suspension culture properties. It exhibits unique characteristics, including its ability to induce T cells to produce a distinctive eosinophil chemotactic factor. Transplantation into immunodeficient hamsters results in aggressive infiltration of skin and bone marrow, rapid tumor growth, and eventual leukemia development. BALL-1 cells are susceptible to the cytotoxic effects of the lectin abrin-a, while the protein GPSM1 promotes tumor growth within the cell line. Cultures can be sustained through fresh medium supplementation or by subcultivation through centrifugation and subsequent resuspension at a 1:2-1:4 ratio.
  • Product Name
    BALL-1
  • Product Type
    Human Leukemia Cell Lines
  • Species
    Human
  • Cell Type
    Lymphocyte-like
  • Source Organ
    Peripheral Blood
  • Disease
    Acute Lymphoblastic Leukemia
  • Product Type
    Human Leukemia Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The BALL-1 cell line emerges as a vital resource in immunological research and the advancement of precise treatments for acute lymphoblastic leukemia. Its relevance extends to serving as a model for pinpointing novel therapeutic targets within this context. By leveraging its unique characteristics, researchers can potentially formulate inhibitors or drugs that effectively differentiate human leukemic cells, thus holding promise for both laboratory investigations and future clinical s.
  • Size/Quantity
    1 vial
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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