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SKU: 0487ATC

BJAB Human Peripheral Blood Lymphoma Specialized Cells

Tumor Cell Lines > Lymphoma Cell Lines

Product Type: Human Lymphoma Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Blood

$1,249.00
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Cell Name: BJAB

Tissue: Peripheral blood. Established from the inguinal tumor of an EBV-negative 5-year-old African girl with Burkitt lymphoma at the preterminal stage.

  • Description
    BJAB cells are a human B cell line established in 1973 from a Burkitt lymphoma tumor of a 5-year-old Caucasian girl. Despite exposure to Epstein-Barr virus (EBV), these cells do not express EBV sequences or antigens. The cells exhibit a round to polymorphic morphology, growing either singly or in large, flat clumps in suspension. BJAB cells have important functions in immunology and cancer research, and are often used in the study of B cell receptor (BCR) signaling pathways, apoptosis mechanisms (such as Fas/CD95-mediated apoptosis), NF-κB activation, and virus (such as EBV/KSHV) and host interactions. Due to its EBV-negative characteristics, it is often used as a control cell line for the analysis of EBV-related carcinogenic mechanisms.
  • Product Name
    BJAB
  • Product Type
    Human Lymphoma Cell Lines
  • Species
    Human
  • Source Organ
    Peripheral Blood
  • Disease
    Burkitt’s Lymphoma
  • Product Type
    Human Lymphoma Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    In tumor research, the BJAB cells are used to explore the pathogenesis of lymphoma, drug sensitivity and resistance, especially the development of targeted therapy for B-cell malignancies. In addition, BJAB cells are highly sensitive to Epstein-Barr virus (EBV) infection and are often used to study EBV latent infection, viral carcinogenic mechanisms, and antiviral drug screening.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    RPMI 1640 + 20% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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