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SKU: 0037APC

Bovine Skeletal Muscle Fibroblasts

Primary Cells > Musculoskeletal Cells

Product Type: Skeletal Muscle Cells

Species: Bovine

Cell Type: Fibroblasts

Source Organ: Muscle

$1,249.00
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Cell Name: Bovine Skeletal Muscle Fibroblasts

  • Description
    Bovine Skeletal Muscle Fibroblasts (BSMFs) are primary interstitial fibroblasts isolated from cattle skeletal muscle. They play a central role in extracellular matrix (ECM) production—including type I and III collagen, fibronectin and proteoglycans—and are essential for muscle integrity and fibrosis regulation. In vitro, BSMFs maintain fibroblast-specific gene expression (e.g., VIM, FSP1) through multiple passages and after cryopreservation. They respond dynamically to TGF‑β1 and myostatin signaling, undergoing myofibroblast transformation with elevated α‑SMA and matrix remodeling capacity. These traits make BSMFs valuable for studies on muscle repair, fibrosis, cultivated meat scaffolds, and tissue-engineering platforms.
  • Product Name
    Bovine Skeletal Muscle Fibroblasts
  • Product Type
    Skeletal Muscle Cells
  • Species
    Bovine
  • Cell Type
    Fibroblasts
  • Source Organ
    Skeletal Muscle
  • Disease
    Normal
  • Product Type
    Skeletal Muscle Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Bovine Skeletal Muscle Fibroblasts are widely used in tissue-engineering and fibrotic disease models to investigate extracellular matrix (ECM) deposition, fibroblast-to-myofibroblast transition, and scaffold development. They serve as feeder cells in co-culture systems, secrete collagen and growth factors, and aid in creating biomimetic scaffolds for cultivated meat. Additionally, BSMFs are applied in muscle fibrosis research, responding to TGF‑β1/myostatin to model fibrotic ECM changes and evaluate anti-fibrotic agents.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Bovine Skeletal Muscle Fibroblasts Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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