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SKU: 0803ATC

BT-474 Human Breast Ductal Cancer Epithelial Cells

Tumor Cell Lines > Breast Cancer Cell Lines

Product Type: Human Breast Cancer Cell Lines

Species: Human

Cell Type: Epithelial Cells

Source Organ: Breast

$1,249.00
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Cell Name: BT-474

The BT-474 line was isolated by E. Lasfargues and W.G. Coutinho from a solid, invasive ductal carcinoma of the breast.

  • Description
    BT-474 is a human breast tumor cell line that was originally isolated from the breast tissue of a 60-year-old white female patient with invasive ductal carcinoma. BT-474 exhibits epithelial-like morphology and adherent/patchy culture properties. BT-474 is shown as aneuploid expression with the chromosome mode numbers of 55. These cells express high levels of progesterone receptors (PR), estrogen receptor positive (ER), and human epidermal growth factor receptor 2 (HER2). BT-474 is tumorigenic in nude mice. These characteristics make it a powerful model for studying hormone-responsive breast cancer.
  • Product Name
    BT-474
  • Product Type
    Human Breast Cancer Cell Lines
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Breast
  • Disease
    Ductal Cancer
  • Product Type
    Human Breast Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The BT-474 cell line finds valuable s in preclinical breast cancer research, offering a direct link to real patients with matching genetic profiles. This model proves indispensable in drug discovery endeavors, facilitating the development of innovative targeted treatments for breast cancer. Its utilization spans from investigating small molecules and antibodies to refining cell-based therapies, enhancing the prospects of advancing effective interventions for breast cancer patients.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    RPMI 1640 + 20% FBS + 10 ug/mL Human Insulin
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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