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SKU: 0891ATC

C3A Human Specialized Cells

Tumor Cell Lines > Liver Cancer Cell Lines

Product Type: Human Liver Cancer Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Other

$1,249.00
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Cell Name: C3A

C3A is clonal derivative of Hep G2 that was selected for strong contact inhibition of growth, high albumin production, high production of alpha fetoprotein (AFP) and ability to grow in glucose deficient medium.

  • Description
    C3A, also known as HepG2/C3A, a derivative of Hep G2, is a hepatoblastoma cell line that was derived from the liver tissue of a 15-year-old white male patient with hepatocellular carcinoma. C3A exhibits epithelial-like morphology and adherent culture properties. These cells have the characteristics of strong contact inhibition of growth, and they are able to grow in a glucose-deficient medium. C3A expresses a high level of albumin and alpha-fetoprotein (AFP) protein, with AFP secretion decreasing and albumin secretion increasing upon cell confluence.
  • Product Name
    C3A
  • Product Type
    Human Liver Cancer Cell Lines
  • Species
    Human
  • Product Type
    Human Liver Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The C3A cell line finds diverse s in cancer, toxicology, and immuno-oncology research. Its utility extends to studying hepatocyte function and targeted protein expression. Moreover, C3A cells serve as a foundation for creating sophisticated in vitro three-dimensional (3D) cell-based systems that closely mimic in vivo cellular behavior. Particularly, the utilization of HepG2/C3A spheroids presents a highly sensitive and promising model for genotoxicity assessments and environmental studies, enhancing the accuracy of evaluating genotoxic activities in both individual chemicals and intricate environmental samples.
  • Size/Quantity
    1 vial
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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