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SKU: 0761APC

C57BL/6 Mouse Alveolar Epithelial Cells


Primary Cells > Lung & Airway Cells

Product Type: Mouse Primary Cells

Species: C57BL/6 Mouse

Cell Type: Epithelial Cells

Source Organ: Lung


Regular price $1,249.00

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Cell Name: C57BL/6 Mouse Alveolar Epithelial Cells

  • Description
    C57BL/6 Mouse Alveolar Epithelial Cells are primary cells isolated from the lung tissue of C57BL/6 mice, comprising two subtypes: alveolar type I (AT1) and type II (AT2) epithelial cells. AT1 cells exhibit a flattened squamous morphology with thin cytoplasmic extensions, covering over 95% of the alveolar surface, while AT2 cells are cuboidal and occupy the remaining 5%. Functionally, AT1 cells mediate gas exchange and regulate fluid balance through aquaporin-dependent osmotic permeability and ion transport. Both subtypes express high levels of the ACE2 receptor, a critical entry point for SARS-CoV-2. Their physiological relevance makes them valuable for modeling alveolar-specific pathologies, including viral infections and surfactant dysfunction .
  • Product Name
    C57BL/6 Mouse Alveolar Epithelial Cells
  • Product Type
    Mouse Primary Cells
  • Species
    C57BL/6 Mouse
  • Cell Type
    Epithelial
  • Source Organ
    Alveolar
  • Disease
    Normal
  • Product Type
    Mouse Primary Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    C57BL/6 Mouse Alveolar Epithelial Cells serve as a valuable tool for investigating lung diseases like pulmonary fibrosis. With applications ranging from genomic and proteomic analyses to ex vivo culturing, they offer insights into diverse biological processes. Particularly suited for exploring the lung’s fibrogenic microenvironment and the adaptability of these cells within it, they hold promise for advancing epithelial cell-targeted therapies addressing pulmonary fibrosis and related conditions.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    C57BL/6 Mouse Alveolar Epithelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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