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C57BL/6 Mouse Esophageal Epithelial Cells

Primary Cells > Intestine & Gastrointestinal Cells

Product Type: Mouse Primary Cells

Species: C57BL/6 Mouse

Cell Type: Epithelial Cells

Source Organ: Esophagus

$1,249.00
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Cell Name: C57BL/6 Mouse Esophageal Epithelial Cells

  • Description
    The C57BL/6 mouse esophageal epithelial cell line is derived from the esophagus of healthy wild-type mice, without disease background. They retain typical epithelial markers, including E-cadherin and ZO-1, confirmed via immunofluorescence. The cells show a normal diploid karyotype (2n=40), verified by G-banding, and are recommended for use below passage 20 to maintain phenotype. Non-tumorigenic and non-metastatic, they are free of mouse-specific viruses such as ectromelia and mouse hepatitis virus. This cell line is widely used to study esophageal epithelial-stromal interactions and diseases such as eosinophilic esophagitis. Its non-cancerous, genetically stable nature makes it ideal for investigating fibrotic responses and epithelial barrier dysfunction in esophageal tissues.
  • Product Name
    C57BL/6 Mouse Esophageal Epithelial Cells
  • Product Type
    Mouse Primary Cells
  • Species
    C57BL/6 Mouse
  • Cell Type
    Epithelial
  • Source Organ
    Esophagus
  • Disease
    Normal
  • Product Type
    Mouse Primary Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    C57BL/6 mouse esophageal epithelial cells serve as a valuable model system for studying the intricate interactions between epithelial and stromal components. These cells are crucial in unraveling the cellular heterogeneity present in the mouse esophagus. By utilizing C57BL/6 mouse esophageal epithelial cells, researchers can gain insights into the mechanisms driving progressive fibrostenotic diseases, such as eosinophilic esophagitis fibrosis, and deepen our understanding of epithelial biology. This cell model provides a robust platform for investigating the underlying mechanisms and identifying potential therapeutic targets for these diseases affecting the esophageal epithelium.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    C57BL/6 Mouse Esophageal Epithelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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