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SKU: 0383APC

Canine Aortic Endothelial Cells

Primary Cells > Heart & Vascular Cells

Product Type: Canine Primary Cells

Species: Canine

Cell Type: Endothelial Cells

Source Organ: Aorta

$1,249.00
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Cell Name: Canine Aortic Endothelial Cells

  • Description
    Canine primary aortic endothelial cells (CnAOEC) are derived from canine aortic tissue. Following the primary culture, these cells are cryopreserved. Endothelial cells serve as the natural barrier between blood and tissue, and are involved in the regulation of vasomotion, angiogenesis, and inflammation. They are metabolically active, producing autocrine and paracrine signaling molecules, supporting bidirectional molecular transport, and maintaining dynamic adhesion between cells and between cells and the extracellular matrix. In vitro, these cells should be avoided repeated freezing and thawing during culture.
  • Product Name
    Canine Aortic Endothelial Cells
  • Product Type
    Canine Primary Cells
  • Species
    Canine
  • Cell Type
    Endothelial
  • Source Organ
    Aortic
  • Disease
    Normal
  • Product Type
    Canine Primary Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Dogs are considered valuable animal models for studying human diseases due to their physiological and genetic similarities to humans. They naturally develop cardiovascular conditions, such as heart failure, mitral valve disease, and arrhythmias, which progress in ways that closely resemble human disease. As such, CnAOECs (Canine Aortic Endothelial Cells) serve as a translational model for investigating the pathogenesis, progression, and treatment of human cardiovascular diseases. These cells can also be used to screen for candidate genes that may serve as novel endothelial cell markers.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Canine Aortic Endothelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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