Free delivery over $100 Learn more

30 days return period Learn more
SKU: 0864ATC

CCD-18Co Human Colon Fibroblasts Cell Line

Tumor Cell Lines > Colon Cancer Cell Lines

Product Type: Human Colon Cancer Cell Lines

Species: Human

Cell Type: Fibroblasts

Source Organ: Intestine

$1,249.00
Size

Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Cell Name: CCD-18Co

Human colon fibroblast, normal, ethnicity: Black. Derived from biopsy colon tissue of a black female infant (2.5 Months old). CCD 18Lu and CCD-18Co were derived from the lung and colon respectively from the same patient; This has been confirmed by STR profile.

  • Description
    CCD-18Co cell line is a human colon fibroblast cell line derived from normal colon tissue of a 2.5-month-old Black female infant. These cells exhibits a fibroblast-like morphology and grow in an adherent monolayer. Subculturing is recommended at a split ratio of 1:2 to 1:3 every 2 to 3 days. CCD-18Co retains a diploid karyotype, typical for normal human fibroblasts. Functionally, the cell line demonstrate responsiveness to cytokine stimulation, including increased prostaglandin E2 (PGE2) production and upregulated COX-2 expression upon IL-1βtreatment. The stable phenotype and responsiveness make it a validated model for studying colon fibroblast physiology, extracellular matrix (ECM) interactions, and inflammation signaling pathways.
  • Product Name
    CCD-18Co
  • Product Type
    Human Colon Cancer Cell Lines
  • Species
    Human
  • Cell Type
    Fibroblast
  • Source Organ
    Colon
  • Disease
    Normal
  • Product Type
    Human Colon Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    CCD-18Co, a non-transformed cell line, plays a central role in cancer and inflammation research. It is commonly used as a normal control in cancer studies, particularly for delineating epithelial-stromal interactions in co-culture systems. The cell line is instrumental in modeling the tumor microenvironment, enabling analysis of fibroblast-mediated signaling and extracellular matrix (ECM) remodeling. Additionally, CCD-18Co cells serves as a valuable in vitro model for investigating pathological fibrosis and inflammatory responses in the colon, providing key insights into conditions such as colitis and colon-associated fibrotic disorders.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    EMEM + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

Payment & Security

Payment methods

    Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

    • Visit our support center

      Expert help & advice

    • Check your order status

      Updates & tracking

    • Returns & exchanges

      All you need to know

    • Price-match guarantee

      Our promise to you