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SKU: 0491APC

CD1 Cerebellar Granule Cells Mouse

Primary Cells > Brain & Nervous System Cells

Product Type: Cerebellar Granule Cells

Species: CD1 Mouse

Cell Type: Neurons

Source Organ: Brain

$1,249.00
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Cell Name: CD1 Cerebellar Granule Cells

  • Description
    CD1 Cerebellar Granule Cells (CGCs) are primary neurons isolated from the cerebellum of CD1 mouse pups. In culture, they develop mature characteristics, such as an extensive network of neurites, expression of excitatory amino acid receptors, and synthesis and release of glutamate. CGCs rely on N-methyl-D-aspartate (NMDA) receptor activity for survival and differentiation both in vivo and in vitro. Functionally, CGCs integrate sensory and motor inputs via mossy fibers, relaying processed information to Purkinje cells, thereby fine-tuning motor coordination, learning, and cognitive functions. These cells are extensively used for studying neuronal apoptosis, ataxia, fetal alcohol spectrum disorders, and other neurodegenerative disease models.
  • Product Name
    CD1 Cerebellar Granule Cells
  • Product Type
    Cerebellar Granule Cells
  • Species
    CD1 Mouse
  • Cell Type
    Neurons
  • Source Organ
    Cerebellum
  • Disease
    Normal
  • Product Type
    Cerebellar Granule Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    CD1 Cerebellar Granule Cells (CGCs) are widely used to investigate neurodevelopment, synaptic plasticity, and neuroprotection mechanisms. They are valuable for modeling neurodegenerative diseases such as ataxia and fetal alcohol spectrum disorders. CGCs can be cultured to study excitatory receptor expression and glutamate synthesis, making them ideal for exploring neuronal survival mechanisms. Additionally, they provide a robust model for studying synaptic function and the molecular pathways involved in cerebellar development and degeneration.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    CD1 Cerebellar Granule Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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