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SKU: 031NTC

CHO-K1 Hamster Ovary Epithelial Cells

Non-Tumor Continuous Cell Lines > Ovarian Cell Lines

Product Type: Mouse Ovarian Cell Lines

Species: Hamster, Chinese

Cell Type: Epithelial Cells

Source Organ: Ovary

$1,249.00
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Cell Name: CHO-K1

CHO-K1 Cell Line is from hamster, Chinese; Strain: Chinese; Tissue: ovary; Morphology: epitherial like; Profile: CHO-K1 cells are useful for isolation of nutritionally deficient mutants.

  • Description
    CHO-K1 cells are a subclone of the CHO cell line, derived from an adult Chinese hamster ovary biopsy in 1957. CHO-K1 cells are widely used in biopharmaceutical production due to their rapid growth, ease of culture, and minimal chromosomal abnormalities. However, they lack the gene for proline synthesis, making them reliant on external proline for growth. These cells exhibit morphological changes in response to cholera toxin and show resistance to Poliovirus, Modoc virus, and Buttonwillow virus. Under specific culture conditions, these cells can be passaged for 10-15 generations, making them suitable for long-term experimental applications. They also express multiple glycosylation genes, which affect the quality of therapeutic proteins.
  • Product Name
    CHO-K1
  • Product Type
    Mouse Ovarian Cell Lines
  • Species
    Hamster, Chinese
  • Cell Type
    Epithelial
  • Source Organ
    Ovary
  • Product Type
    Mouse Ovarian Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The CHO-K1 cell line can be engineered to grow as adherent or suspension cells and have gained regulatory approval for the production of therapeutic recombinant proteins. CHO-K1 cells are an excellent host system for producing various biologics, including growth factors, hormones, monoclonal antibodies, interferons, and enzymes. Moreover, they are utilized in in vitro cancer research, especially for studying ovarian cancer. The popularity of CHO-K1 cells in protein production is due to favorable traits like rapid growth, easy cultivation, and genomic stability.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    Ham’s F12 + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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