SKU: 0166ATC

COV362 Human Ovary Ovarian Epithelial Endometroid Cancer Specialized Cells

Tumor Cell Lines > Ovarian Cancer Cell Lines

Product Type: Human Ovarian Cancer Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Ovary

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Ship on dry ice.

Cell Name: COV362

A human ovarian epithelial-endometroid carcinoma cell line established from a pleural effusion. Anchorage-independent growth in agar has been reported. The cell line COV362.4 is a subclone of this cell line.

  • Description
    COV362 is a human ovarian epithelial-endometrioid carcinoma cell line that was originally isolated from the pleural effusion of an age-unspecified female patient with high-grade ovarian serous adenocarcinoma (HGSOC). COV362 exhibits epithelial-like morphology with polygonal and fusiform cell shape and adherent culture properties. It demonstrates anchorage-independent growth in agar and exhibits prominent structural rearrangements in chromosomes 1, 3, 7, and 11. COV362 carrying TP53 and BRCA1 gene mutation. It is tumorigenic in a nude mouse model but is normally considered as either subcutaneous or intraperitoneal xenografts.
  • Product Name
    COV362
  • Product Type
    Human Ovarian Cancer Cell Lines
  • Species
    Human
  • Source Organ
    Ovary
  • Disease
    Ovarian Epithelial Endometroid Cancer
  • Product Type
    Human Ovarian Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The COV362 cell line finds diverse s, serving as a valuable tool in the creation of xenograft models for preclinical drug development insights, exploring the impact of estrogen supplementation on ovarian cancer behavior and targeted therapeutic responses. Additionally, it proves crucial in genomic analyses, reflecting the prevalent high-grade serous ovarian cancer (HGSOC) subtype. Moreover, COV362 serves as a robust model for testing potential therapies, including innovative approaches like CAR-T cell therapies.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    DMEM + 2mM Glutamine + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    2

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