SKU: 0024ATC

CT26-OVA Mouse Colon Carcinoma Fibroblasts Cell Line

Tumor Cell Lines > Colon Cancer Cell Lines

Product Type: Mouse Colon Cancer Cell Lines

Species: Mouse

Cell Type: Fibroblasts

Source Organ: Intestine

$1,249.00

Size

1 vial

Care information

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Cell Name: CT26-OVA

Description

The CT26-OVA cell line is a variant of the CT26 murine colon carcinoma cell line that has been engineered to stably and highly express ovalbumin (OVA), a well-known immunogenic antigen protein.
Product Name

CT26-OVA
Product Type

Mouse Colon Cancer Cell Lines
Species

Mouse
Cell Type

Fibroblast
Source Organ

Colon
Disease

Carcinoma
Product Type

Mouse Colon Cancer Cell Lines
Growth Conditions

37 °C, 5% CO2
Application

The CT26-OVA cell line is a valuable tool in immuno-oncology research, offering a robust model for studying immune responses and evaluating cancer therapeutics. Engineered to stably express the highly immunogenic ovalbumin (OVA) antigen, CT26-OVA cells enhance tumor-immune interactions, making them ideal for screening immunotherapies. These cells can establish tumors in vivo, enabling efficacy studies in animal models, particularly for immune checkpoint inhibitors like anti-PD-1. Researchers can use CT26-OVA to explore antigen presentation, cytotoxic T-lymphocyte (CTL) recognition, and tumor cell death, providing insights into mechanisms of immune evasion and the development of novel cancer treatments. This cell line serves as a powerful platform for advancing the field of cancer immunotherapy.
Size/Quantity

1 vial
Recommended Medium And Supplement

RPMI 1640 + 10% FBS
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Shipping Conditions

Dry Ice
Storage

Liquid Nitrogen
Biosafety Level

1

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