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SKU: 0358ATC

EBC-1 Human Lung Specialized Cells

Tumor Cell Lines > Lung Cancer Cell Lines

Product Type: Human Lung Cancer Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Lung

$1,249.00
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Cell Name: EBC-1

EBC-1 Cell Line is from human; Sex: M; Tissue: lung (cancer); Profile: squamous cell carcinoma.

  • Description
    EBC-1 is a human squamous cell lung carcinoma cell line derived from the lung tissue. It originated from explant cultures of squamous, adenocarcinoma, and small cell carcinoma types. The cells exhibit epithelial morphology and grow adherently in EMEM medium at 37°C and 5% CO₂. EBC-1 cells carry a p53 mutation (p.Glu171Ter, c.511G>T), exhibit heterogeneity in EGFR mutations, and harbor Met gene amplification, resulting in overexpression of Met receptor tyrosine kinase, crucial for tumor growth, invasion, and metastasis. These cells are tumorigenic and, when implanted in hamsters, demonstrate high lung metastasis, making them an ideal model for studying metastatic mechanisms. EBC-1 cells are BSL-1 and free of HPV, HIV, and EBV. Their high viability, sterility, and consistent phenotype ensure reliable results for chemosensitivity and targeted therapeutic research in lung squamous cell carcinoma.
  • Product Name
    EBC-1
  • Product Type
    Human Lung Cancer Cell Lines
  • Species
    Human
  • Source Organ
    Lung
  • Product Type
    Human Lung Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    EBC-1 cells, when implanted into hamsters, act as an effective model for investigating human pulmonary carcinoma. Researchers can utilize this model to investigate the mechanisms underlying metastasis and assess drug sensitivity of anticancer compounds. The EBC-1 model enables the exploration of new targets for cancer therapy and allows the screening for effective inhibitors to determine their ability to suppress pulmonary metastasis. This cell line provides a platform for studying the efficacy of potential therapeutic interventions and aids in the design of innovative therapeutic approaches for lung cancer.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    EMEM + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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