SKU: 0564ATC

H357 Human Tongue Oral Squamous Cell Carcinoma Specialized Cells

Tumor Cell Lines > Head & Neck Cancer Cell Lines

Product Type: Human Tongue Cancer Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Oral Cavity

$1,249.00

Size

1 vial

Care information

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Cell Name: H357

Description

Established from a squamous cell carcinoma (SCC) of the tongue (20mm) of a 74 year-old male patient. STNMP stage I, well differentiated, node negative tumour. Mutant p53, codon 110 exon 4, G to A; the previously reported mutant Ha-ras status of this cell line: codon: 13, G to A, codon 61, A-G is under investigation. This cell line is highly responsive to TGF (Transforming growth factor )-β and undergoes epithelial to mesenchymal transition. It expresses high levels of TGF-β1. Fahey et al (1996). Tumourigenic in athymic nude mice on subcutaneous injection and non-tumorigenic on orthotopic injection. Haplotype information: A*02,A*31; B*40,B*44; Cw*03,Cw*05
Product Name

H357
Product Type

Human Tongue Cancer Cell Lines
Species

Human
Source Organ

Tongue
Disease

Oral Squamous Cell Cancer
Product Type

Human Tongue Cancer Cell Lines
Growth Conditions

37 °C, 5% CO2
Size/Quantity

1 vial
Recommended Medium And Supplement

DMEM+ Ham’s F12 (1:1) + 10% FBS
Shipping Conditions

Dry ice
Storage

Liquid Nitrogen
Biosafety Level

2

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