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SKU: 015SPC

H9-derived Oligodendrocyte Progenitor Cells (OPCs) Human

Stem & Progenitor Cells > Progenitor Cells

Product Type: Nervous Cells

Species: Human

Cell Type: Glial Cells

Source Organ: Other

$1,249.00
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Cell Name: H9-derived Oligodendrocyte Progenitor Cells (OPCs)

  • Description
    Human H9-derived Oligodendrocyte Progenitor Cells (OPCs) are derived from NIH approved H9 human embryonic stem cells (hESCs). These hESC-derived OPCs proliferate as an adherent cell monolayer and greater than 70% express the appropriate early-to-intermediate oligodendrocyte markers, including O4, NG2, Olig2, Sox10 and GalC. Upon growth factor withdrawal, Human OPCs spontaneously differentiate into mature oligodendrocytes expressing terminally differentiated markers including proteolipid protein (PLP), myelin basic protein (MBP), and myelin oligodendrocyte glycoprotein (MOG). Spontaneous differentiation leads to approximately 30% of the cells expressing PLP, MBP and MOG while the remaining 70% express mostly neuronal markers, MAP2 and beta III-tubulin with very little to no astrocytes (<5% GFAP-positive cells) observed. Human OPCs can be used for a variety of research applications including studies of neurotoxicity, co-culture applications and screening for molecules that induce or inhibit preferential differentiation to mature oligodendrocytes.
  • Product Name
    H9-derived Oligodendrocyte Progenitor Cells (OPCs)
  • Product Type
    Nervous Cells
  • Species
    Human
  • Cell Type
    Oligodendrocyte
  • Source Organ
    H9 Cells
  • Disease
    Normal
  • Product Type
    Nervous Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    H9-derived Oligodendrocyte Progenitor Cell Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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