SKU: 0551ATC

H9 Human Lymphoblasts Cell Line

Tumor Cell Lines > Lymphoma Cell Lines

Product Type: Human Lymphocytes Cell Lines

Species: Human

Cell Type: Lymphoblasts

Source Organ: Other

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Cell Name: H9

Human T cell. Clonal derivative of the T-cell line HUT 78 derived from the blood of a patient with Sezary syndrome. The clone was selected due to its suitability for the isolation and continuous high level production.

  • Description
    H9 is a derivative of the Hut 78 cell line that was originally isolated from the haematopoietic and/or lymphoid tissue of a 53-year-old white male patient with Sezary syndrome. H9 exhibits lymphoblast-like morphology and suspension culture properties. H9 which is a highly aggressive form of cutaneous T-cell lymphoma. This cell line stands out for its exceptional ability to consistently isolate and generate various HIV variants from the blood samples of individuals with AIDS and pre-AIDS conditions. With a near triploid state, it typically possesses 69 chromosomes, although this count can range from 58 to 74. Higher ploidy instances occur minimally at 2.5%. H9 are express CD4; HLA A1, B62, C3, DR4, DQ3 antigen.
  • Product Name
    H9
  • Product Type
    Human Lymphocytes Cell Lines
  • Species
    Human
  • Cell Type
    Lymphoblast
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The H9 cell line serves as a crucial tool in various s, notably as a target for investigating HIV-1 infection dynamics. It enables the observation of changes in infected cells induced by HIV-1, encompassing alterations in protein expression and host cell antigen presence. Furthermore, it facilitates the evaluation of anti-AIDS agents’ inhibitory effects on vital HIV-1 processes like binding, reverse transcription, and replication, providing invaluable insights into potential therapeutic strategies.
  • Size/Quantity
    1 vial
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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