SKU: 0717ATC

HCT-8 Human Epithelial Cells

Tumor Cell Lines > Colon Cancer Cell Lines

Product Type: Human Colon Cancer Cell Lines

Species: Human

Cell Type: Epithelial Cells

Source Organ: Other

$1,249.00

Size

1 vial

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Cell Name: HCT-8

The HCT-8 line is identical to the HRT-18 cell line. The cells are positive for keratin by immunoperoxidase staining.

Description

HCT-8 is a human colorectal adenocarcinoma cell line that was originally isolated from the colon of a 67-year-old Caucasian male patient with ileocecal adenocarcinoma. HCT-8 exhibits epithelial-like morphology and adherent culture properties. Immunoperoxidase staining confirmed that HCT-8 cells are positive for cytokeratin expression. This cell line is tumorigenic.
Product Name

HCT-8
Product Type

Human Colon Cancer Cell Lines
Species

Human
Cell Type

Epithelial
Product Type

Human Colon Cancer Cell Lines
Growth Conditions

37 °C, 5% CO2
Application

The HCT-8 cell line is a valuable tool in both cancer and toxicology research. It is widely used to study drug resistance and to elucidate the mechanisms underlying chemoresistance. These cells also support investigations into cell death pathways, including apoptosis and necrosis. Notably, HCT-8 cells are used in the construction of compartmentalized three-dimensional (3D) intestinal models, offering an alternative culture system for continuous cell propagation and enabling detailed studies of gastrointestinal diseases and drug responses.
Size/Quantity

1 vial
Shipping Conditions

Dry Ice
Storage

Liquid Nitrogen
Biosafety Level

1

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