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SKU: 0045ATC

HeLa Human Cervix Cervical Cancer Epithelial Cells

Tumor Cell Lines > Uterine Cancer Cell Lines

Product Type: Human Uterine Cancer Cell Lines

Species: Human

Cell Type: Epithelial Cells

Source Organ: Cervix

$1,249.00
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Cell Name: HeLa

The cells are positive for keratin by immunoperoxidase staining. HeLa cells have been reported to contain human papilloma virus 18 (HPV-18) sequences. P53 expression was reported to be low.

  • Description
    HeLa is a human cervical carcinoma cell line that was originally isolated from the cervix tissue of a 31-year-old Black female patient with cervical adenocarcinoma; it’s the first established human immortal cell line. HeLa exhibits epithelial-like morphology and adherent culture properties. The stemline karyotype of HeLa is around 76–80, with a large proportion of chromosome mutations. The HeLa cell line demonstrates five distinct HPV-18 integration loci, with three insertions identified on the long arm of chromosome 8 (8q24) and two additional integration sites mapped to structurally altered derivative chromosomes: der(5)t(5;22;8)(q11;q11q13;q24) and der(22)t(8;22)(q24;q13).
  • Product Name
    HeLa
  • Product Type
    Human Uterine Cancer Cell Lines
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Cervix
  • Disease
    Cervical Cancer
  • Product Type
    Human Uterine Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    HeLa cells exhibit diverse s in infectious disease and biomedical research, including the study of infectious diseases and sexually transmitted diseases, as well as bioproduction. Their utility extends to investigating virus replication, assembly, and pathogenesis, aiding in antiviral strategy development. Moreover, HeLa cells serve as transfection hosts for gene function and regulation studies, recombinant protein production, and gene therapy investigations. These cells have been instrumental in pivotal scientific achievements, including the isolation of Hepatitis B, polio vaccine development, and uncovering chromosome structure, marking their indispensable contribution to groundbreaking discoveries.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    EMEM + 2mM Glutamine + 1% Non Essential Amino Acids + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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