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SKU: 0013ATC

HMVII Human Vagina Melanoma Epithelial Cells


Tumor Cell Lines > Melanoma Cell Lines

Product Type: Human Melanoma Cell Lines

Species: Human

Cell Type: Epithelial Cells

Source Organ: Vagina


Regular price $1,249.00

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Cell Name: HMVII

Human vaginal maligant melanoma. Established from a vaginal malignant melanoma of a 65 year-old female with blood type B. Cells produce melanin and can support the replication of influenza C virus.

  • Description
    HMVII is a human melanoma cell line that was originally isolated from the vagina of a 65-year-old female patient with malignant melanoma. HMVII exhibits epithelial-like morphology and adherent culture properties. Studies have shown that in HMVII cells with intact IFN signaling, ruxolitinib can suppress the IFN response in melanoma cell lines with functional JAK/STAT signaling, thereby sensitizing melanoma to oncolytic vesicular stomatitis virus.
  • Product Name
    HMVII
  • Product Type
    Human Melanoma Cell Lines
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Vagina
  • Disease
    Melanoma
  • Product Type
    Human Melanoma Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The HMVII cell line can be used in cytotoxicity experiments, such as testing sensitivity to OV, herpes simplex virus 1 (HSV1-dICP0), and vesicular stomatitis virus (VSV-Δ51). It is also valuable for identifying biomarkers that predict immunotherapy response and resistance mechanisms. Additionally, these cells can be used to study signaling pathways and screen for optimal drugs or drug combinations to treat vaginal malignant melanoma.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    Ham’s F10 or RPMI 1640 + 2mM Glutamine + 10-20% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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