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SKU: 392BIC

Human Acute Lymphoid Leukemia Peripheral Blood Mononuclear Cells (Newly Diagnosed/Untreated)

Blood and Immune Cells & Products > Peripheral Blood Mononuclear Cells (PBMCs)

Product Type: Diseased Human Peripheral Blood Mononuclear Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: Human Acute Lymphoid Leukemia Peripheral Blood Mononuclear Cells (Newly Diagnosed/Untreated)

  • Description
    Human Acute Lymphoid Leukemia Peripheral Blood Mononuclear Cells (Newly Diagnosed/Untreated) are primary mononuclear cells isolated from the peripheral blood of patients diagnosed with Acute Lymphoid Leukemia (ALL). Collected via gradient centrifugation and PBS dilution, the population includes lymphocytes (T cells, B cells, NK cells) and monocytes, key for hematologic immune responses. These cells exhibit apoptosis resistance and distinct gene expression, including increased caspases-8/9 and pro-apoptotic protein BAK compared to healthy PBMCs. Typically grown in suspension culture (37°C, 5% CO₂), these cells can also be sorted for further studies on leukemia pathogenesis, immune interactions, and therapeutic screening. They are tested negative for mycoplasma, bacteria, yeast, and fungi, cryopreserved for optimal viability. Ideal for immunophenotyping, apoptosis analysis, and drug sensitivity testing in ALL.
  • Product Name
    Human Acute Lymphoid Leukemia Peripheral Blood Mononuclear Cells (Newly Diagnosed/Untreated)
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Species
    Human
  • Cell Type
    Mononuclear Cell
  • Source Organ
    Peripheral Blood
  • Disease
    Acute Lymphoid Leukemia
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Acute Lymphoid Leukemia Peripheral Blood Mononuclear Cells (Newly Diagnosed/Untreated) can be used to study disease mechanisms, such as the self-renewal of leukemia stem cells, the development of drug resistance, and immune escape mechanisms. In addition, these cells can also be used for drug development, through in vitro experiments to evaluate the killing effects of targeted drugs, chemotherapy regimens, or CAR-T cell therapies on primary tumor cells.
  • Size/Quantity
    1 vial
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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