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SKU: 1072APC

Human Adrenal Cortical Cells

Primary Cells > Endocrine Cells

Product Type: Adrenal Cells

Species: Human

Cell Type: Cortical Cell

Source Organ: Adrenal Gland

$1,249.00
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Cell Name: Human Adrenal Cortical Cells

  • Description
    Human Adrenal Cortical Cells are primary cells derived from pooled human fetal adrenal cortical tissue from multiple donors of mixed gender. The fetal adrenal cortex comprises two zones—the fetal and definitive zones—while the adult cortex includes the zona glomerulosa, zona fasciculata, and zona reticularis. These cells, typically grown as adherent monolayers, are organized in cord-like structures in vivo and display morphological heterogeneity, including smaller round cells in the zona glomerulosa and polyhedral cells in the fasciculata and reticularis. They actively secrete hormones, cytokines, and peptides, and express key steroidogenic enzymes such as CYP11B1, CYP17A1, and StAR. The cells interact with local immune related signals such as IL-1, IL-6, and VIP released by adrenal macrophages.
  • Product Name
    Human Adrenal Cortical Cells
  • Product Type
    Adrenal Cells
  • Species
    Human
  • Cell Type
    Cortical Cell
  • Source Organ
    Adrenal
  • Disease
    Normal
  • Product Type
    Adrenal Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Adrenal Cortical Cells serve as a valuable model for investigating adrenal disorders like adrenal insufficiency, Cushing’s syndrome, Conn’s syndrome, and adrenocortical carcinoma. By studying these cells, researchers can uncover the molecular and biochemical mechanisms regulating adrenal steroidogenesis. This knowledge can lead to better diagnostics and targeted therapies. Moreover, human adrenal cortical cells provide a platform to explore the effects of chemicals on adrenal hormone synthesis. Researchers can assess how various compounds impact hormone production, shedding light on how external factors influence adrenal function.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Adrenal Cortical Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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