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SKU: 331BIC

Human Allergy-related Peripheral Blood Mononuclear Cells

Blood and Immune Cells & Products > Peripheral Blood Mononuclear Cells (PBMCs)

Product Type: Diseased Human Peripheral Blood Mononuclear Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: Human Allergy-related Peripheral Blood Mononuclear Cells

  • Description
    Human Allergy-related Peripheral Blood Mononuclear Cells are a heterogeneous population of immune cells derived from the peripheral blood of individuals with allergic conditions, primarily including lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, PBMCs are small, round cells. Allergy-related PBMCs play a central role in hypersensitivity reactions. Th2 cells drive allergic inflammation by secreting IL-4, IL-5, and IL-13, which promote IgE production by B cells and activate eosinophisl. Regulatory T (Treg) cells may exhibit impaired function in allergies, failing to suppress aberrant immune responses.
  • Product Name
    Human Allergy-related Peripheral Blood Mononuclear Cells
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Species
    Human
  • Cell Type
    Mononuclear Cell
  • Source Organ
    Peripheral Blood
  • Disease
    Allergy
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Allergy-related Peripheral Blood Mononuclear Cells can be used to analyze the activation characteristics of Th2 immune response, the regulatory mechanism of IgE production, and immune tolerance defects. They can also be used to evaluate the immunomodulatory effects of anti-allergic drugs (such as glucocorticoids, biological targeted agents), or to test the in vitro effectiveness of new immunotherapies.
  • Size/Quantity
    1 vial
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen

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