Free delivery over $100 Learn more

30 days return period Learn more
SKU: 1037APC

Human Alveolar Macrophages Non-Small Cell Lung Cancer

Primary Cells > Lung & Airway Cells

Product Type: Pulmonary Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Lung

$1,249.00
Size

Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Cell Name: Human Alveolar Macrophages

  • Description
    Human Alveolar Macrophages are terminally differentiated, non-proliferative primary cells typically isolated from bronchoalveolar lavage fluid of healthy donors or patients with lung diseases. They reside in the lung parenchyma, guarding the alveolar-blood barrier by scavenging pathogens, particles, and pollutants. These mononuclear phagocytes exhibit an irregular, flattened morphology and adhere to culture vessels, often requiring M-CSF or GM-CSF for in vitro viability. They secrete cytokines and chemokines such as TNF-α and IL-1β to initiate inflammation and recruit neutrophils, and phagocytose apoptotic or necrotic cells. Alveolar macrophages express markers like CD68, CD11c, and CD206. Their functional responses are mediated through receptors like TLR4, activating NF-κB signaling. Phenotypic shifts occur in disease states—e.g., an M2-like profile in asthma.
  • Product Name
    Human Alveolar Macrophages
  • Product Type
    Pulmonary Cells
  • Species
    Human
  • Cell Type
    Macrophage
  • Source Organ
    Alveolar
  • Disease
    Normal/Non-Small Cell Lung Cancer
  • Product Type
    Pulmonary Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Alveolar Macrophages can be used as an in vitro model to study lung immune mechanisms, pathogen-host interactions and intercellular communication, which helps to gain a deeper understanding of the initiation and regulation of lung innate immunity and adaptive immunity. These cells can also be used to explore the pathogenesis of lung diseases (such as pneumonia, lung cancer, and chronic obstructive pulmonary disease) and further understand the functional changes of macrophages in these diseases.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Alveolar Macrophages Medium Kit
  • Quality Control
    All cell lots test negative for HIV-1, HBV, HCV, mycoplasma, yeast, fungi, and other pathogens.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

Payment & Security

Payment methods

    Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

    • Visit our support center

      Expert help & advice

    • Check your order status

      Updates & tracking

    • Returns & exchanges

      All you need to know

    • Price-match guarantee

      Our promise to you