SKU: 354BIC

Human Alzehimer’s Disease Peripheral Blood Mononuclear Cells

Blood and Immune Cells & Products > Peripheral Blood Mononuclear Cells (PBMCs)

Product Type: Diseased Human Peripheral Blood Mononuclear Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

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Cell Name: Human Alzehimer’s Disease Peripheral Blood Mononuclear Cells

  • Description
    Human Alzheimer’s Disease Peripheral Blood Mononuclear Cells (PBMCs) are immune cells isolated from the peripheral blood of patients with Alzheimer’s disease (AD), primarily comprising lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, PBMCs are typically small, round cells. PBMCs play a critical role in immune regulation and neuroinflammation. AD-associated PBMCs often exhibit abnormal cytokine secretion (e.g., elevated TNF-α, IL-6), and altered T-cell responses, reflecting systemic immune dysfunction linked to AD pathogenesis. These cells are implicated in the peripheral inflammatory cascade that may exacerbate central nervous system pathology, including β-amyloid deposition and tau hyperphosphorylation.
  • Product Name
    Human Alzehimer’s Disease Peripheral Blood Mononuclear Cells
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Species
    Human
  • Cell Type
    Mononuclear Cell
  • Source Organ
    Peripheral Blood
  • Disease
    Alzehimer’s Disease
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Alzheimer’s Disease Peripheral Blood Mononuclear Cells can be used to study how the peripheral immune system participates in the neurodegenerative process of AD through pathways such as inflammatory factor release and cell migration, especially their role in impaired β-amyloid clearance and neuroinflammation. They can also be used to evaluate the efficacy of anti-inflammatory drugs or immunomodulatory agents.
  • Size/Quantity
    1 vial
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen

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