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SKU: 1171APC

Human Astrocytes-Retina Glial Cells

Primary Cells > Eye Cells

Product Type: Ocular Cells

Species: Human

Cell Type: Glial Cells

Source Organ: Eye

$1,249.00
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Cell Name: Human Astrocytes-Retina

  • Description
    Human Retinal Astrocytes are derived from the human retina. Following the primary culture, these cells are cryopreserved. Predominantly localized to the nerve fiber layer and optic nerve head, they provide structural support to retinal ganglion cell axons, regulate extracellular ion and neurotransmitter, and contribute to blood-retinal barrier integrity. These cells are also implicated in the pathogenesis of various retinal disorders, including glaucoma, diabetic retinopathy, and ischemic retinopathies. In vitro, repeated freezing and thawing should be avoided during the culture process.
  • Product Name
    Human Astrocytes-Retina
  • Product Type
    Ocular Cells
  • Species
    Human
  • Cell Type
    Astrocyte
  • Source Organ
    Retina
  • Disease
    Normal
  • Product Type
    Ocular Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Retinal Astrocytes are responsible for maintaining the retinal microenvironment and providing structural support. They are involved in retinal glucose metabolism, supplying retinal neurons with the necessary nutrients for oxidative metabolism. They also play a role in regulating proper immune responses. In retinopathy, astrocytes adopt defensive programs, which are disease- and context-specific, and involve the activation of thousands of genes to maintain retinal homeostasis. Studies have shown that astrocytes can trigger inflammation in glaucoma. Under glaucoma, they become reactive and change their phenotypes into neurotoxic ones. They release neurotoxic factors such as cytokines and chemokines, damaging the axons of retinal ganglion cells.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Astrocytes-Retina Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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