SKU: 1282APC

Human Brain Microvascular Endothelial Cells

Primary Cells > Brain & Nervous System Cells

Product Type: Nervous Cells

Species: Human

Cell Type: Endothelial Cells

Source Organ: Brain

Inquire about this product

Delivery and Shipping

Ship on dry ice.

Cell Name: Human Brain Microvascular Endothelial Cells

  • Description
    Human Brain Microvascular Endothelial Cells (HBMECs) are isolated from the human brain tissues. Brain Microvascular Endothelial Cells (BMECs) form the interface between circulating blood and neural tissue, maintaining the blood-brain barrier (BBB) and regulating the CNS (central nervous system) homeostasis. Endothelial cells (ECs) are flat with a central, elongated nucleus at the microscopic level. Studies have found that compounds such as glucose, amino acids and exogenous drugs can enter brain tissue through special transport proteins expressed in BMECs, including transferrin receptor, insulin-like growth factor receptor, and angiotensin receptor . These cells also express tight junction proteins like claudin-5, occludin, and ZO-1 that form the structural basis of the BBB’s selective permeability.
  • Product Name
    Human Brain Microvascular Endothelial Cells
  • Product Type
    Nervous Cells
  • Species
    Human
  • Cell Type
    Endothelial
  • Source Organ
    Brain
  • Disease
    Normal
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Brain Microvascular Endothelial Cells (HBMECs) can be used to study the mechanism of pathogens (such as bacteria and viruses) penetrating the BBB and to evaluate the delivery efficiency of drugs to the central nervous system. In the study of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease, HBMECs are used to analyze the association between vascular dysfunction and pathological development.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Brain Microvascular Endothelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

Payment & Security

Payment methods

    Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

    Product inquiry

    Tell us what you need and our team will get back to you with pricing and availability.

    • Visit our support center

      Expert help & advice

    • Check your order status

      Updates & tracking

    • Returns & exchanges

      All you need to know

    • Price-match guarantee

      Our promise to you