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SKU: 326BIC

Human C. Difficile Peripheral Blood Mononuclear Cells Clostridioides Difficile Infection

Blood and Immune Cells & Products > Peripheral Blood Mononuclear Cells (PBMCs)

Product Type: Diseased Human Peripheral Blood Mononuclear Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: Human C. Difficile Peripheral Blood Mononuclear Cells

  • Description
    Human Clostridioides Difficile Peripheral Blood Mononuclear Cells are derived from peripheral blood, mainly comprising lymphocytes (T cells, B cells, NK cells) and monocytes. In Clostridium difficile infection (CDI), PBMCs play a key role through immune regulation: T cells (such as Th1/Th17) mediate inflammatory responses, while regulatory T cells (Treg) inhibit excessive immune responses; monocytes differentiate into macrophages and participate in pathogen clearance. PBMCs in CDI patients may show abnormal activation, resulting to cytokine storms (such as increased IL-1β and TNF-α), which are related to the severity of the disease.
  • Product Name
    Human C. Difficile Peripheral Blood Mononuclear Cells
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Species
    Human
  • Cell Type
    Mononuclear Cell
  • Source Organ
    Peripheral Blood
  • Disease
    Clostridioides difficile
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human.Clostridioides Difficile Peripheral Blood Mononuclear Cells can be used to study the immunopathological mechanisms associated with Clostridium difficile infection (CDI). It can also be used to test the effects of antibiotics, immunomodulators (such as IL-10, TNF-α inhibitors) or new therapies (such as fecal microbiota transplantation) on immune cell function and evaluate their efficacy and safety. In addition, PBMCs can also be used for biomarker screening.
  • Size/Quantity
    1 vial
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen

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