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SKU: 1273APC

Human Cardiac Microvascular Endothelial Cells

Primary Cells > Heart & Vascular Cells

Product Type: Cardiac Cells

Species: Human

Cell Type: Endothelial Cells

Source Organ: Heart

$1,249.00
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Cell Name: Human Cardiac Microvascular Endothelial Cells

  • Description
    The endothelial cells modulate vascular tone by release of several endothelium-derived contracting and relaxing factors, by regulation and degradation of vasoactive peptides, and by enzymes located on the endothelial surface. These functions vary within different spaces, within blood vessels of different organs, and between the macro- and microvasculations. Cardiac microvascular endothelial cells (CMEC) exert physiological and pathophysiological effects on the function of cardiac myocytes. They release cardioactive substances including nitric oxide, endothelin-1, prostanoids, adenylpurines, natriuretic peptides, and other agents, that modify and regulate cardiac myocyte function. Such effects of endothelial cells have been demonstrated both in vivo and in vitro. CMEC also possess enzymatic activities, in particular ACE/kininase activity, which can alter local levels of angiotensin II and bradykinin in the heart. HCMEC Research Laboratories are isolated from human heart tissue. HCMEC are cryopreserved after purification and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HCMEC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII and CD31 (P-CAM) and by uptake of DiI-Ac-LDL. HCMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HCMEC are guaranteed to further expand for 15 population doublings at the conditions provided by our research lab.
  • Product Name
    Human Cardiac Microvascular Endothelial Cells
  • Product Type
    Cardiac Cells
  • Species
    Human
  • Cell Type
    Endothelial
  • Source Organ
    Heart
  • Disease
    Normal
  • Product Type
    Cardiac Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Cardiac Microvascular Endothelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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