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SKU: 173BIC

Human CD4+/CD25+ Regulatory T Cells


Blood and Immune Cells & Products > Peripheral Blood Cells

Product Type: Immune Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Bone Marrow


Regular price $1,249.00

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Cell Name: Human CD4+/CD25+ Regulatory T Cells

  • Description
    Human CD4+/CD25+ Regulatory T Cells (Tregs), formerly known as suppressor T cells, are a subpopulation of T cells. They are derived from progenitor cells in bone marrow and play an important role in maintaining immune homeostasis. Tregs act by immunosuppression or downregulation of other immune cells, preventing autoimmune disease and chronic inflammation. However, its suppressiveness also limits some beneficial immune responses during microorganism infection and anti-tumor activity. Naturally occurring Tregs (nTregs) express CD4, CD25 and a key transcription factor forkhead box P3 (FOXP3). Human CD4+/CD25+ Regulatory T Cells also downregulate the expression of CD127 (or IL-7R), which can be used as Treg cells marker during identification and purification.
    Why Choose Human CD4+/CD25+ Regulatory T Cells?
    Human CD4+/CD25+ Regulatory T Cells were isolated from peripheral blood using positive or negative immunomagnetic selection.
    All Treg cells were cryopreserved in cell culture media kit. Each vial contains 1 million cells or can be customized on request.
    All donors have passed QC test and been tested negative for HIV, HBV, HCV, mycoplasma, and chlamydia.
    We provide our customers with optimal culture protocols, which has been optimized by our technicians and guarantee timely technical support if any questions. Our cell product has high purity, is easily accessible and ready-to-use in scientific research and laboratories.
  • Product Name
    Human CD4+/CD25+ Regulatory T Cells
  • Product Type
    Immune Cells
  • Species
    Human
  • Cell Type
    T Cell
  • Source Organ
    Bone Marrow
  • Disease
    Normal
  • Product Type
    Immune Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Tregs can be used in modelling immune responses to help understand autoimmune disorders. Their immunosuppressive roles can be useful in providing insight into immune therapeutics such as treatment for HIV and malaria infection. Human CD4+/CD25+ Regulatory T Cells can also be used to study tumor immunity in cancer treatment, facilitate transplantation and would healing.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human CD4+/CD25+ Regulatory T Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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