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SKU: 1265APC

Human Cerebellar Granule Cells

Primary Cells > Brain & Nervous System Cells

Product Type: Nervous Cells

Species: Human

Cell Type: Neurons

Source Organ: Brain

$1,249.00
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Cell Name: Human Cerebellar Granule Cells

  • Description
    Human Cerebellar Granule Cells (GCs) originate from neural precursor cells in the rhombic lip and are localized in the cerebellar granule layer after migration. Following migration, they become one of the most abundant neuron types in the central nervous system. Morphologically, GCs are small in size and densely arranged. As the main excitatory neurons in the cerebellar cortex, GCs are responsible for integrating sensory motor information from the spinal cord and brainstem, and participate in motor coordination, posture control and cognitive function through the parallel fiber-Purkinje cell pathway. This circuitry enables GCs to play crucial roles in motor coordination, fine movement control, and posture maintenance. Emerging evidence also suggests their involvement in specific cognitive functions. Recent studies have revealed that GCs exhibit synaptic plasticity at their mossy fiber synapses, which may contribute to motor learning and adaptation.
  • Product Name
    Human Cerebellar Granule Cells
  • Product Type
    Nervous Cells
  • Species
    Human
  • Cell Type
    Granule Cell
  • Source Organ
    Brain
  • Disease
    Normal
  • Product Type
    Nervous Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Cerebellar Granule Cells have been studied extensively and often used as a model system for neuronal development, neuron survival/apoptosis and toxicity. They can also be used to build computational model of adult neuron network and development.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Cerebellar Granule Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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