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SKU: 1262APC

Human Choroid Plexus Endothelial Cells

Primary Cells > Brain & Nervous System Cells

Product Type: Nervous Cells

Species: Human

Cell Type: Endothelial Cells

Source Organ: Brain

$1,249.00
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Cell Name: Human Choroid Plexus Endothelial Cells

  • Description
    Human Choroid Plexus Endothelial Cells (HCPEnC) are derived from healthy human brain tissue. Following primary culture, these cells are cryopreserved. Immunofluorescence analysis confirms the expression of endothelial markers PECAM1 and vWF. They also express several tight junction proteins, including ZO-1, OCLN, CLDN1, and CLDN5. Human Choroid Plexus Endothelial Cells form capillary-like structures. In vitro, these cells exhibit limited proliferative capacity and cannot be passaged. Repeated freezing and thawing during culture should be avoided.
  • Product Name
    Human Choroid Plexus Endothelial Cells
  • Product Type
    Nervous Cells
  • Species
    Human
  • Cell Type
    Endothelial
  • Source Organ
    Choroid Plexus
  • Disease
    Normal
  • Product Type
    Nervous Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Choroid Plexus Endothelial Cells are valuable tools for advancing the understanding of choroid plexus (CP) organ functions, particularly the complex interactions between endothelial and epithelial cells. Located in the brain’s ventricles, the CP is a highly vascularized structure that forms a critical interface between the cerebrospinal fluid (CSF) and the blood, linking the central nervous system (CNS) with the rest of the body. The endothelial cells within the CP contribute to modulating the blood-CSF barrier (BCSFB), which is essential for maintaining brain homeostasis. Human Choroid Plexus Endothelial Cells serve as in vitro models for studying CP functions and the BCSFB. They are also instrumental in researching disease mechanisms, such as those involved in meningitis, and developing therapeutic approaches targeting these conditions.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Choroid Plexus Endothelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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