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SKU: 1261APC

Human Choroid Plexus Epithelial Cells

Primary Cells > Brain & Nervous System Cells

Product Type: Nervous Cells

Species: Human

Cell Type: Epithelial Cells

Source Organ: Brain

$1,249.00
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Cell Name: Human Choroid Plexus Epithelial Cells

  • Description
    Human Choroid Plexus Epithelial Cells (HCPEpCs) are specialized polarized epithelial cells isolated from the choroid plexus, the brain structure responsible for cerebrospinal fluid (CSF) production. These cuboidal-shaped cells form tight junctions and exhibit characteristic microvilli-covered apical surfaces. They express key markers including transthyretin (TTR), aquaporin-1 (AQP1), and cytokeratin 18 (CK18). HCPEpCs play crucial roles in maintaining the blood-CSF barrier, regulating ion transport, and secreting neuroprotective factors. They are valuable tools for studying neurodevelopmental disorders (e.g., hydrocephalus), neurodegenerative diseases (e.g., Alzheimer’s disease), and neuroinflammatory processes. Choroid plexus epithelial cells serve as a physiologically relevant choroid plexus model, with the choroid plexus epithelium and associated choroidal cells enabling studies of barrier function, CSF secretion, and central nervous system homeostasis.
  • Product Name
    Human Choroid Plexus Epithelial Cells
  • Product Type
    Nervous Cells
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Choroid Plexus
  • Disease
    Normal
  • Product Type
    Nervous Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Choroid Plexus Epithelial Cells can be used to explore the mechanism of substance transport across barriers, the regulation of cerebrospinal fluid secretion, and neuro-immune interactions. These cells can also be used to evaluate the permeability and toxicity of central nervous system (CNS) drugs and optimize brain-targeted drug delivery strategies.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Choroid Plexus Epithelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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