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SKU: 115BIC

Human Dendritic Cells

Blood and Immune Cells & Products > Peripheral Blood Cells

Product Type: Nervous Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: Human Dendritic Cells

  • Description
    Human dendritic cells (DCs) are specialized antigen-presenting cells derived from peripheral blood of healthy human donors. These cells are critical in initiating adaptive immune responses by activating naïve T cells and promoting their differentiation into effector cells, while also helping to maintain immune tolerance. In culture, human DCs are non-proliferative and survive for up to 7 days as immature dendritic cells (iDCs) when treated with IL-4 and GM-CSF, and can further differentiate into mature dendritic cells with TNF-α and IL-1β. Morphologically, they exhibit dendritic projections and express a characteristic surface marker profile including CD11c⁺, CD86⁺, CD80⁺, HLA-DR⁺, and CD14⁻, confirmed via flow cytometry. While karyotype analysis is not typically performed, they are widely used in cancer immunotherapy, infectious disease models, and autoimmune disorder research due to their potent antigen-presenting capacity and immunomodulatory role.
  • Product Name
    Human Dendritic Cells
  • Product Type
    Nervous Cells
  • Species
    Human
  • Cell Type
    DC Cell
  • Source Organ
    Blood
  • Disease
    Normal
  • Product Type
    Nervous Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human dendritic cells (DCs) can be used to simulate pathogen-host interactions (such as HIV, SARS-CoV-2) in infectious disease research and evaluate vaccine efficacy through antigen cross-presentation. In addition, in the study of autoimmune diseases, DCs help to elucidate the mechanism of immune tolerance destruction (such as rheumatoid arthritis) and are used to test tolerogenic DC-based therapies to inhibit abnormal immune activation.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Dendritic Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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