Free delivery over $100 Learn more

30 days return period Learn more
SKU: 1321APC

Human Dermal Fibroblasts, Adult

Primary Cells > Skin Cells

Product Type: Dermal Cells

Species: Human

Cell Type: Fibroblasts

Source Organ: Skin

$1,249.00
Size

Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Cell Name: Human Dermal Fibroblasts, Adult

  • Description
    Human Dermal Fibroblasts, Adult are primary cells isolated from the dermal layer of human skin. These cells exhibit an adherent culture properties, forming confluent monolayers with a dense, overlapping growth pattern. Functionally, HDFa synthesize extracellular matrix components like collagen and elastin, orchestrate wound healing through fibronectin-mediated migration, and interact with epidermal cells during tissue repair and hair follicle development. Human Dermal Fibroblasts demonstrate mesenchymal stem cell-like properties, expressing surface markers CD73, CD90, and CD105. They serve as cellular substrates for induced pluripotent stem cell (iPSC) reprogramming using the Yamanaka transcription factors (Oct3/4, Sox2, Klf4, c-Myc).
  • Product Name
    Human Dermal Fibroblasts, Adult
  • Product Type
    Dermal Cells
  • Species
    Human
  • Cell Type
    Fibroblast
  • Source Organ
    Dermal
  • Disease
    Normal
  • Product Type
    Dermal Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    HDFa serve as a versatile model system for investigating various facets of cell physiology and have been prominently featured in numerous research works, especially within the realms of skin biology and reprogramming studies. These fibroblasts find application in diverse areas such as pathogen response, skin aging, wound healing, gene delivery, and skin-related disorders like scleroderma. Their utility extends to research involving ECM protein analysis, collagen metabolism, cosmetics, skin therapy, and model development, encompassing an array of multidisciplinary research avenues.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Dermal Fibroblasts, Adult Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

Payment & Security

Payment methods

    Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

    • Visit our support center

      Expert help & advice

    • Check your order status

      Updates & tracking

    • Returns & exchanges

      All you need to know

    • Price-match guarantee

      Our promise to you