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SKU: 1246APC

Human Epidermal Melanocytes-dark

Primary Cells > Skin Cells

Product Type: Melanocyte

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Skin

$1,249.00
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Cell Name: Human Epidermal Melanocytes-dark

  • Description
    The melanocyte is a neural crest-derived cell that localizes in humans to several organs including the epidermis, eye, inner ear and leptomeninges. The failure of melanocytes to migrate to these locations explains the association of congenital white spotting of the skin (piebaldism) with heterochromia (the juxtaposition of different colors) in the iris as well as congenital deafness in Waardenburg syndrome. In the skin, melanocytes synthesize and transfer melanin pigments to surrounding keratinocytes, leading to skin pigmentation and protection against solar exposure. Recent progress in basic cell-culture technology, along with an improved understanding of culture requirements, has led to the success in culturing of this special cell type in pure population and the discovery of a novel melanocyte-specific gene, msg1, which encodes a nuclear protein and is associated with pigmentation.HEM-d Research Laboratories are isolated from neonate human epidermis. HEM-d are cryopreserved on passage one culture and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HEM-d are characterized by immunofluorescent method with antibodies to fibronectin and NGF-receptor (p75). HEM-d are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HEM-d are guaranteed to further expand for 15 population doublings in the condition provided by our research lab.
  • Product Name
    Human Epidermal Melanocytes-dark
  • Product Type
    Melanocyte
  • Species
    Human
  • Cell Type
    Melanocyte
  • Source Organ
    Epidermal
  • Disease
    Normal
  • Product Type
    Melanocyte
  • Growth Conditions
    37 °C, 5% CO2
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Epidermal Melanocytes-dark Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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