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Human Esophageal Smooth Muscle Cells

Primary Cells > Intestine & Gastrointestinal Cells

Product Type: Esophageal Cells

Species: Human

Cell Type: Smooth Muscle Cells

Source Organ: Esophagus

$1,249.00
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Cell Name: Human Esophageal Smooth Muscle Cells

  • Description
    Smooth muscle is responsible for the contractility of hollow organs, such as blood vessels, the gastrointestinal tract, the bladder, and the uterus. Its structure differs greatly from that of skeletal muscle. The human esophagus contains three layers of muscle in its walls, the outer longitudinal and inner circular layers of the main muscular coat and the muscular layer of the mucosa. Visceral smooth muscle cells makes up all three layers along the entire organ except for the most rostral few centimeters. Smooth muscle contraction is critical to peristalsis in the human esophagus and the contraction may be mediated by activation of phospholipase through two distinct mechanisms (increased intracellular Ca2+ and G protein activation) and activating PKCepsilon-dependent mechanisms. In vitro study also shows that cultured human esophageal smooth muscle cells express voltage-dependent Na(+) channels.HESMC Research Laboratories are isolated from the human esophagus. HESMC are cryopreserved at secondary culture and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HESMC are characterized by immunofluorescent method with antibodies to Α-smooth muscle actin and desmin. HESMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HESMC are guaranteed to further expand for 15 population doublings at the condition provided by our research lab.
  • Product Name
    Human Esophageal Smooth Muscle Cells
  • Product Type
    Esophageal Cells
  • Species
    Human
  • Cell Type
    Smooth Muscle Cell
  • Source Organ
    Esophagus
  • Disease
    Normal
  • Product Type
    Esophageal Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Esophageal Smooth Muscle Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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