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SKU: 1097APC

Human Fallopian Tube Epithelial Cells

Primary Cells > Reproductive System Cells

Product Type: Female Reproductive Cells

Species: Human

Cell Type: Epithelial Cells

Source Organ: Fallopian Tube

$1,249.00
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Cell Name: Human Fallopian Tube Epithelial Cells

  • Description
    Human Fallopian Tube Epithelial Cells (FTECs) are primary cells derived from the mucosal epithelium of human fallopian tubes, predominantly isolated from the distal fimbrial region. These cells include distinct polarized epithelial subtypes such as ciliated cells and secretory cells, along with minor populations of intercalary and undifferentiated cells. These cells are typically cryopreserved at the earliest passage to maintain their native characteristics. Functionally, hFTECs are integral to gamete transport, secrete antimicrobial factors, and immune surveillance, in part via Toll-like receptor 3 (TLR3)-mediated responses. Importantly, FTECs – particularly secretory cells – are implicated in the pathogenesis of high-grade serous ovarian carcinoma (HGSOC), making them a focal point in cancer research. These cells express epithelial markers such as cytokeratin-17 (CK-17) and PAX8. FTECs cannot be serially passaged in vitro. Their dual role in bothreproductive physiology and carcinogenesis make them a powerful model for studying HGSOC progression, tubal microenvironment and epithelial transformation.
  • Product Name
    Human Fallopian Tube Epithelial Cells
  • Product Type
    Female Reproductive Cells
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Fallopian Tube
  • Disease
    Normal
  • Product Type
    Female Reproductive Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Fallopian Tube Epithelial Cells (FTEC) are essential for research into cellular and molecular physiology of the female reproductive tract. They play a pivotal role in unraveling the mechanisms to pathogens, inflammatory signals, and hormonal changes. These cells are invaluable for studying normal fallopian tube epithelial biology and serve as foundational models for studying the orgins and progressions of diseases, including high-grade serous ovarian carcinoma (HGSOC), helping to unravel the early molecular events of serous carcinogenesis. Researchers leverage FTECs for investigating gene expression profiles, transcriptomics and proteomic shifts under various risk factors, and impact of hormonal and environmental stimuli on epithelial homeostasis, providing fresh insights into their regenerative responses to hormonal cues.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Fallopian Tube Epithelial Cells Medium Kit
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen

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