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SKU: 1061APC

Human Gingival Fibroblasts

Primary Cells > Oral & Craniofacial Cells

Product Type: Oral Cells

Species: Human

Cell Type: Fibroblasts

Source Organ: Oral Cavity

$1,249.00
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Cell Name: Human Gingival Fibroblasts

  • Description
    Human Gingival Fibroblasts (HGFs) are isolated from healthy human gingival tissue. Morphologically, these cells are spindle-shaped or star-shaped and grow adherently when cultured in vitro. They are responsible for synthesizing extracellular matrix components such as collagen fibers and elastic fibers, and participate in the repair and regeneration of gingival tissue. HGFs also play a key role in sustaining inflammation response by interacting with pathogens and their component lipopolysaccharide (LPS) in periodontal disease [1-4]. Under inflammatory conditions, HGFs can secrete various cytokines and chemokines, such as IL-6 and IL-8, which amplify the immune response and contribute to periodontal tissue destruction. Additionally, their ability to modulate immune cell activity makes them crucial players in both wound healing and chronic inflammatory processes like periodontitis.
  • Product Name
    Human Gingival Fibroblasts
  • Product Type
    Oral Cells
  • Species
    Human
  • Cell Type
    Fibroblast
  • Source Organ
    Gingival
  • Disease
    Normal
  • Product Type
    Oral Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Gingival Fibroblasts can be used as an in vitro cell model to study the pathogenesis of periodontal disease, especially to explore the molecular mechanism of fibroblast dysfunction in diseases such as gingival atrophy and periodontitis. These cells can also be used to construct bioactive scaffolds to promote the regeneration of gingival defects.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Gingival Fibroblasts Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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