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SKU: 1233APC

Human Hair Inner Root Sheath Cells


Primary Cells > Skin Cells

Product Type: Hair Cells

Species: Human

Cell Type: Epithelial Cells

Source Organ: Skin


Regular price $1,249.00

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Cell Name: Human Hair Inner Root Sheath Cells

  • Description
    The inner root sheath (IRS) of human hair follicles consists of three concentric cell layers: the cuticle, Huxley’s layer, and Henle’s layer. All three layers are formed from the peripheral mass of matrix cells in the hair bulb. The formation of the IRS during the evolution of mammalian epidermis allowed the physiological exit of hairs produced inside the skin. Immunohistochemical staining indicates the human IRS cells express K6irs1, K6irs2, K6irs3, and K6irs4, the inner-root-sheath-specific type II epithelial keratins. In situ hybridization study found FGF-22 mRNA in the skin was preferentially expressed in the inner root sheath of the hair follicle. Therefore, FGF-22 is expected to be a unique FGF that plays a role in hair development.HHFIRSC Research Laboratories are isolated from human hair follicle inner root sheaths. HHFIRSC are cryopreserved at primary culture and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HHFIRSC are characterized by their mesenchymal cell morphology and immunofluorescent method with antibody to fibronectin and CD105. HHFIRSC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HHFIRSC are guaranteed to further expand for 15 population doublings at the condition provided by our research lab.
  • Product Name
    Human Hair Inner Root Sheath Cells
  • Product Type
    Hair Cells
  • Species
    Human
  • Cell Type
    Root Sheath Cell
  • Source Organ
    Hair
  • Disease
    Normal
  • Product Type
    Hair Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Hair Inner Root Sheath Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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