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SKU: 1052APC

Human Hepatocytes

Primary Cells > Liver & Biliary Cells

Product Type: Hepatic Cells

Species: Human

Cell Type: Hepatocytes

Source Organ: Liver

$1,249.00
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Cell Name: Human Hepatocytes

  • Description
    Human Hepatocytes are isolated from the human liver tissue. Hepatocytes are the main parenchymal cells of the liver, occupying most of the liver’s volume (about 80%). These cells are rich in Golgi apparatus and mitochondria, enabling them to perform essential functions in metabolism, protein synthesis, and detoxification.Studies have shown that in non-alcoholic fatty liver disease (NAFLD), hepatocytes undergo a series of metabolic changes such as the decreased ketone body production and increased glycolysis. In vitro, human hepatocytes display a polygonal morphology, form tight junctions, and exhibit adherent monolayer growth. Hepatocytes also have immune functions and can produce and secrete innate immune proteins such as Complement C3, Lectin MBL, MAp19, MASP1, 2 3, and C-reactive protein (CRP), which can activate innate immunity, directly eliminate pathogens, and coordinate the immune system to fight pathogens
  • Product Name
    Human Hepatocytes
  • Product Type
    Hepatic Cells
  • Species
    Human
  • Cell Type
    Hepatocyte
  • Source Organ
    Liver
  • Disease
    Normal
  • Product Type
    Hepatic Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Hepatocytes can be used to study the mechanism of liver disease. These cells can also be used for safety assessment (such as prediction of liver toxicity) and metabolic kinetics research during the drug development stage, helping to improve the reliability of clinical trials.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Hepatocytes Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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