SKU: 361BIC

Human HIV Peripheral Blood Mononuclear Cells Human Immunodeficiency Virus Infection

Blood and Immune Cells & Products > Peripheral Blood Mononuclear Cells (PBMCs)

Product Type: Diseased Human Peripheral Blood Mononuclear Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

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Cell Name: Human HIV Peripheral Blood Mononuclear Cells

  • Description
    Human HIV Peripheral Blood Mononuclear Cells are a heterogeneous population of immune cells isolated from the peripheral blood of HIV-infected patients, mainly including lymphocytes (such as T cells, B cells, NK cells) and monocytes.Typical round mononuclear lymphocytes and monocytes; suspension culture; non-adherent. PBMCs play an important role in immune response: T cells mediate cellular immunity, B cells produce antibodies, and monocytes differentiate into macrophages or dendritic cells to participate in antigen presentation . HIV infection destroys CD4+ T cell function, leading to immunodeficiency, and then triggering acquired immunodeficiency syndrome (AIDS) .HIV infection causes progressive depletion and dysfunction of CD4+ T cells, resulting in immunodeficiency and development of AIDS. PBMCs act as reservoirs for latent and active virus.
  • Product Name
    Human HIV Peripheral Blood Mononuclear Cells
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Species
    Human
  • Cell Type
    Mononuclear Cell
  • Source Organ
    Peripheral Blood
  • Disease
    Human Immunodeficiency Virus
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human HIV Peripheral Blood Mononuclear Cells can be used as an in vitro cell model to study viral pathogenic mechanisms. They can also be used to analyze HIV-specific T cell responses, including the killing activity of CD8+ T cells and CD4+ T cell dysfunction. Besides, these cells can be applied to study the role of B cell antibody production and monocyte-derived antigen presenting cells in HIV infection.
  • Size/Quantity
    1 vial
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen

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