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SKU: 323BIC

Human Idiopathic Pulmonary Fibrosis (IPF) Peripheral Blood Mononuclear Cells

Blood and Immune Cells & Products > Peripheral Blood Mononuclear Cells (PBMCs)

Product Type: Diseased Human Peripheral Blood Mononuclear Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: Human Idiopathic Pulmonary Fibrosis (IPF) Peripheral Blood Mononuclear Cells

  • Description
    Human Idiopathic Pulmonary Fibrosis (IPF) Peripheral Blood Mononuclear Cells are immune cells isolated from the peripheral blood of Idiopathic Pulmonary Fibrosis (IPF) patients, primarily comprising lymphocytes (T cells, B cells, NK cells) and monocytes. These cells play key roles in immune regulation, inflammation, and fibrosis progression in IPF. Monocytes differentiate into profibrotic macrophages, secreting TGF-β and PDGF to activate fibroblasts, while aberrant T-cell responses exacerbate collagen deposition. IPF-PBMCs are linked to chronic inflammation, aberrant wound healing, and progressive lung scarring, with altered cytokine profiles (elevated IL-4, IL-13, IL-17A) contributing to disease pathogenesis.
  • Product Name
    Human Idiopathic Pulmonary Fibrosis (IPF) Peripheral Blood Mononuclear Cells
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Species
    Human
  • Cell Type
    Mononuclear Cell
  • Source Organ
    Peripheral Blood
  • Disease
    Idiopathic Pulmonary Fibrosis
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Idiopathic Pulmonary Fibrosis (IPF) Peripheral Blood Mononuclear Cells can be used to study the immune pathogenesis of IPF. These cells can also be used to evaluate the immunomodulatory effects of existing anti-fibrotic drugs (such as nintedanib and pirfenidone), and to screen new therapeutic drugs targeting specific inflammatory pathways.
  • Size/Quantity
    1 vial
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen

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