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Human Inflammatory Bowel Disease Peripheral Blood Mononuclear Cells

Blood and Immune Cells & Products > Peripheral Blood Mononuclear Cells (PBMCs)

Product Type: Diseased Human Peripheral Blood Mononuclear Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: Human Inflammatory Bowel Disease Peripheral Blood Mononuclear Cells

  • Description
    Human Inflammatory Bowel Disease Peripheral Blood Mononuclear Cells are isolated from the peripheral blood of patients with inflammatory bowel disease (IBD), primarily consisting of lymphocytes (T cells, B cells, NK cells) and monocytes. These cells play important roles in immune regulation: T cells mediate adaptive immune responses, B cells produce antibodies, and monocytes can differentiate into macrophages or dendritic cells to participate in antigen presentation and proinflammatory cytokine release. In IBD (including Crohn’s disease and ulcerative colitis), PBMCs exhibit an abnormally activated state characterized by enhanced Th1/Th17 cell polarization and impaired regulatory T cell (Treg) function. This imbalance leads to elevated secretion of proinflammatory cytokines (TNF-α, IL-6) that drive chronic intestinal inflammation.
  • Product Name
    Human Inflammatory Bowel Disease Peripheral Blood Mononuclear Cells
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Species
    Human
  • Cell Type
    Mononuclear Cell
  • Source Organ
    Peripheral Blood
  • Disease
    Inflammatory Bowel Disease
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Inflammatory Bowel Disease Peripheral Blood Mononuclear Cells can be used as an in vitro model to investigate the immunopathogenesis of inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis. These cells can also be used for screening and evaluating novel therapeutic agents, including biologics and small molecule inhibitors targeting specific immune pathways.
  • Size/Quantity
    1 vial
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen

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