Free delivery over $100 Learn more

30 days return period Learn more
SKU: 1051APC

Human Kupffer Cells

Primary Cells > Liver & Biliary Cells

Product Type: Hepatic Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Liver

$1,249.00
Size

Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Cell Name: Human Kupffer Cells

  • Description
    Human Kupffer Cells are isolated from human liver tissue. Kupffer cells are liver-resident macrophages, residing within the sinusoidal lumen. These cells contain endocytic vesicles and abundant lysosomes, and can express several endocytic lectin receptors like C-type lectin receptor CLEC4F, which plays a crucial role in mediating platelet destruction. Kupffer cells possess self-renewal capacity and perform key roles in phagocytosis, immune surveillance, and clearance of bacteria as well as apoptotic or necrotic hepatocytes. Studies have shown that Kupffer cells are implicated in different types of liver damage, such as copper and iron toxicity, alcoholic liver disease, and non-alcoholic fatty liver disease.In addition to CLEC4F, they express classical macrophage surface markers including CD68, CD14, CD163, and F4/80, confirming their identity and phagocytic capability.
  • Product Name
    Human Kupffer Cells
  • Product Type
    Hepatic Cells
  • Species
    Human
  • Cell Type
    Kupffer Cell
  • Source Organ
    Liver
  • Disease
    Normal
  • Product Type
    Hepatic Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Kupffer Cells can be used to study liver immune defense and disease mechanisms. These cells can also be used to study the immune pathological mechanisms of diseases such as non-alcoholic fatty liver disease (NAFLD) and drug-induced liver injury.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Kupffer Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen

Payment & Security

Payment methods

    Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

    • Visit our support center

      Expert help & advice

    • Check your order status

      Updates & tracking

    • Returns & exchanges

      All you need to know

    • Price-match guarantee

      Our promise to you