SKU: 0797APC

Human Liver Microsomes-50 Donors (0.5 mL)

Primary Cells > Liver & Biliary Cells

Product Type: Hepatic Cells

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Liver

$1,249.00

Size

1 vial

Care information

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Cell Name: Human Liver Microsomes-50 Donors (0.5 mL)

Description

Pooled Human Liver Microsomes provide a fully characterized, relevant, reliable and reproducible in vitro tool. Pooled of 50 donors give an economic way of deriving an accurate population representation and may be used to describe the metabolic profile of a drug or drug candidate in high-throughput assays as well as the following other uses:
Conduct studies of metabolic stability (% of original drug remaining over time)
Identify which cytochrome P450 (CYP) enzymes oxidize a drug candidate and which UDP-glucuronosyltransferase (UGT) enzymes are responsible for glucuronidation
Identify, quantify and characterize drug metabolites
Describe a drug’s metabolic pathways
Identify inhibition of cytochrome P450 (CYP) enzymes
Product Name

Human Liver Microsomes-50 Donors (0.5 mL)
Product Type

Hepatic Cells
Species

Human
Source Organ

Liver
Disease

Normal
Product Type

Hepatic Cells
Growth Conditions

37 °C, 5% CO2
Size/Quantity

1 vial
Recommended Medium And Supplement

Human Liver Microsomes-50 Donors (0.5 mL) Medium Kit
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Shipping Conditions

Dry Ice
Storage

Liquid Nitrogen
Biosafety Level

1

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